Artificial Intelligence and the Scientific Method: A Theoretical Examination of Discovery, Explanation and Reproducibility in AI-Driven Science

Authors

  • NWOGBOJI Emmanuel Usulor Veristzon Global Research Lab Author
  • Atolagbe Umar Kawu Veristzon Global Research Lab Author
  • Igwe Emmanuel Sunday Veristzon Global Research Lab Author

DOI:

https://doi.org/10.68854/rccqng25

Keywords:

AI for science, scientific discovery, explanation, reproducibility, philosophy of science, machine learning, research integrity, automated science, epistemology of science

Abstract

Artificial intelligence (AI) is changing the conduct of science. Models predict protein structures and propose materials, generate hypotheses, design and execute experiments, and increasingly assist in writing the papers that report the results. This paper examines the effect of these developments on the scientific method, drawing on the philosophy of science, the research-integrity and reproducibility literatures, and recent work on AI-driven discovery across the natural, engineering and social sciences. It distinguishes three functions of science that AI affects differently: discovery, the identification of what is the case; explanation, the account of why it is the case; and reproducibility, the possibility of independent confirmation. The paper argues that AI substantially accelerates discovery, threatens explanation, because predictive success without mechanistic understanding is now attainable at scale, and complicates reproducibility, since AI-driven results depend on models, data and computing conditions that are seldom reported in full or readily reproduced. It sets out a corresponding division of epistemic labour between human scientists and AI systems and a set of reporting and verification standards for AI-assisted research, and it considers the particular implications for scientific institutions in Africa, which may gain access to discovery capacity previously beyond their means while facing acute risks of irreproducibility and of dependence upon others. It argues that these three effects pull in different directions rather than reinforcing one another, so that the governance of AI-assisted research cannot treat acceleration, understanding and confirmation as a single problem. The paper sets out propositions on where predictive models may stand in for mechanistic explanation and where they may not, and proposes that African scientific institutions adopt explicit standards for the reporting and verification of AI-assisted results as a condition of building research capacity that is independent rather than dependent.

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Published

2026-10-27

How to Cite

Artificial Intelligence and the Scientific Method: A Theoretical Examination of Discovery, Explanation and Reproducibility in AI-Driven Science. (2026). IIAR Journal of Artificial Intelligence and Emerging Technologies, 1(2), 1-9. https://doi.org/10.68854/rccqng25

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